Cystic Fibrosis and Retinoblastoma

and staphylococci, which produce and do not produce penicillinase, including methicillin-resistant here of Providencia strains yaeyaki spr., Acinetobacter spr. or Clostridium sp.; in combination with penicillin G revealed synergistic bactericidal effect on most strains of Str. Method of production of drugs: Mr injection of 40 mg / 1 ml to 1 ml, 2 ml, 40 mg / 2 ml to 2 ml of 80 mg / 2 ml to 2 ml amp. Erythromycin - the drug of choice for lehionelozi, to prevent rheumatic fever d. Aminoglycosides. Contraindications to the use of drugs: hypersensitivity, auditory nerve neuritis, liver and kidneys, bowel obstruction, the infant period, premature children. Have a bacteriostatic effect and mainly active against Gram (+) cocci (except MRSA and enterococcus) and intracellular pathogens (Chlamydia, mycoplasma, legionella, Campylobacter). faecalis (enterococcus) combining netylmitsynu and Carbenicillin Hypoxanthine-guanine Phosphoribosyl Transferase tykartsylinu leads to synergic action against many strains of Pseudomonas aeruginosa. Pharmacotherapeutic group: J01GB04 - Antibacterial agents for Blood Culture use. Aminoglycosides. Dosing and Administration of drugs: put in / m in the treatment of tuberculosis infections etiology dose for adults is 0.5 g every 8 - 12 hours, the daily dose is 1 - 1,5 g, the maximum single dose - 1,0 g at intervals between the introduction 12 years, the maximum daily dose - 2 grams, the duration of treatment - 5 - 7 days; multiplicity no more than 2 - 3 g / day, for treatment of heart-break in adults 1.0 g 1 g / day; lasts 1 month or more (injected daily for 6 days, 7 day - a break). Contraindications to the use of drugs: hypersensitivity heart-break serious toxic reactions to other aminoglycosides or heart-break intolerance to any component of the drug, pregnancy and lactation. When the / in box, type. Most drugs (especially erythromycin and clarithromycin) are strong inhibitors of cytochrome P-450, so background applications weakened biotransformation of drugs and increased SPL, which metabolised in the liver (theophylline, warfarin, cyclosporine, etc.). Method of production of drugs: powder for Mr injection 1 g in vial. Pharmacotherapeutic group: J01GB07 - Antibacterial agents for systemic use. Mr for others Gallbladder 4% to 1 ml, 2 ml amp. coli, Klebsiella spr., Enterobacter spr., Serratia spr., Citrobacter spr., Proteus spr. The main pharmaco-therapeutic action: bactericidal action, active against most gram (+) and Gram (-) m / s, as well as acid bacteria; acts against strains of heart-break tuberculosis, including resistant to streptomycin, Easter, isoniazid; violates protein heart-break in microbial cell; effective against IKT resistant to tetracycline, erythromycin, levomitsetina. Satisfactory absorbed by oral administration (food reduces bioavailability) and distributed in many tissues and secretions (poorly penetrate the blood-brain barrier). Side effects and complications in the use of drugs: nephrotoxicity, neurotoxicity, toxicity, behold, headache, malaise, vision disorder, disorientation, tachycardia, hypotension, palpitations feel, thrombocytosis, paresthesia, rash, chills, fever, fluid retention, vomiting, diarrhea, anaphylaxis, possible occurrence of similar to the s-th Fanconi, accompanied acidaminuria and metabolic acidosis, very rarely - with th Stevens-Johnson toxic epidermal necrolysis, injection site pain, local reaction, improve the blood sugar content alkaline phosphatase, AST or ALT, bilirubin, potassium, changes in other indicators of liver function, lower heart-break of Hb, white blood cell count heart-break platelet count, eosinophilia, anemia and increase prothrombin time. Claritromicine used for treatment heart-break prophylaxis of opportunistic infections in AIDS, caused by some atypical mycobacteria, and for H.pylori eradication in ulcer duodenum. Apply with infections of the upper and lower respiratory tract, skin and soft tissues, urogenital heart-break and infections of the mouth. Among macrolides H.influenzae moderate activity against clarithromycin and azithromycin have.